Wednesday, 26 April 2017

Investigation on Conventional and Cross-linked UHMWPE Artificial Joint Biomaterials Using a BiotriboPOD Method

                           http://mathewsopenaccess.com/orthopedics-current-issue.html


Wear has been recognized as the key factor affecting the long-term performance of artificial joints such as hip, knee and spine prostheses. In this paper, the wear of ultra-high molecular weight polyethylene (UHMWPE) and cross-linked UHMWPE counter with cobalt chromium alloy was investigated using a new BiotriboPOD-Multi wear testing apparatus for orthopedic implant materials. Via this apparatus, an effective testing method for the wear evaluation of orthopedic implants can be achieved.Osteolysis induced by ultra-high molecular weight polyethylene (UHMWPE) wear particles is regarded as an important factor in the long-term durability of total joint arthroplasty. Up to 100,000 micron sized UHMWPE wear particles are released per footstep. 


Such wear particles can activate the immune system as well as be deposited into the surrounding tissue, which results in the lifetime of the most artificial joints limited to about 10-15 years. Therefore, the investigation on the wear performance of UHMWPE material is one of the important research areas in artificial joints. Since material selection and component design are two essential factors in the wear performance and durability of orthopedic implants, both biomaterial and product wear test are needed. Because the tribological property of orthopedic biomaterials has significant influence on the wear performance of implants, the bench wear evaluation of orthopedic biomaterials is regarded as another important testing methodology. A proper bench wear test can be used to develop an understanding of wear mechanisms and the influence of environmental, design, and material parameters on wear behavior. Moreover, due to the low productivity, complex structure and high cost of joint simulator wear testing, a reliable and effective wear testing methodology for orthopedic biomaterials is expected and required. In the tribological evaluation of orthopedic implants, POD testing methods have also been applied. 

However, unfortunately, the conventioncal POD test devices with unidirectional relative motions between a pin and a disk could not reproduce the wear factors obtained in clinic. For example, the wear factors obtained for the most common combination, ultra high molecular weight polyethylene (UHMWPE) against polished CoCrMo alloy in bovine serum are of the order of 10-8 mm3 / Nm whereas the true clinical wear factors measured from retrieved acetabular cups of artificial hip joints are of the order of 10-6 mm3 /Nm. According to the study on the joint movements in human activities, researchers have observed a directional dependence on the wear rate of orthopedic biomaterials. Thus, the multi-directional motion has been regarded as fundamental importance in laboratory wear tests for orthopedic biomaterials. Following this rule, studies on the development of new POD devices for orthopedic biomaterials are being carried out. Saikko developed a high-capacity hip wear simulator of the circular translation pin-on-disk type, call super-CTPOD, which could provide 100 separated test stations and reproduced the wear of artificial hip joints in vitro. The present authors designed a single-station POD apparatus, and validation test results show the wear factor agreed with those obtained in clinic. In this study, the wear performance of conventional ultra high molecular polyethylene (UHMWPE) and cross-linked UHMWPE were investigated by a new BiotriboPOD-Multi method in a long-term testing duration. Wear factors were calculated and compared with clinical results.  

No comments:

Post a Comment